Description

5-Bromo-3-Nitropyridine-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex molecular architectures in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and nitro substituents for bioactivity.
• Material Science: Serves as a building block for creating functionalized polymers, ligands for metal-organic frameworks (MOFs), and advanced electronic materials.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to the reactive bromo and nitro groups.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized heterocyclic dyes and colorants.
• Academic & Contract Research: A valuable reagent for methodological studies and discovery chemistry in university and CRO laboratories.

Basic Information

Item	Details
Product Name	5-Bromo-3-Nitropyridine-2-Carboxylic Acid
CAS No.	954240-89-2
Molecular Formula	C6H3BrN2O4
Molecular Weight	247.00 g/mol
Synonyms	2-Carboxy-5-bromo-3-nitropyridine; 5-Bromo-3-nitro-2-pyridinecarboxylic acid; 5-Bromo-3-nitropicolinic acid; 3-Nitro-5-bromopyridine-2-carboxylic acid; 954240-89-2; 5-Br-3-NO2-Py-2-COOH
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Nitropyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.