Description

2-Bromomethyl-4-Phthalimido-Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its reactive bromomethyl group and phthalimide-protected amine functionality. This compound matters for its critical role as a versatile building block in the synthesis of complex, nitrogen-containing heterocycles, enabling the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its pyridine core for bioactivity.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds and molecular probes used in biochemical and cellular research.
• Ligand and Catalyst Preparation: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of novel polymers and functional materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Bromomethyl-4-Phthalimido-Pyridine
CAS No.	954240-70-1
Molecular Formula	C₁₅H₁₁BrN₂O₂
Molecular Weight	331.17 g/mol
Synonyms	4-(1,3-Dioxoisoindolin-2-yl)-2-(bromomethyl)pyridine; 2-(Bromomethyl)-4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)pyridine; 2-(Bromomethyl)-4-phthalimidopyridine; N-(2-(Bromomethyl)pyridin-4-yl)phthalimide; 954240-70-1; 2-Bromomethyl-4-phthalimido-pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromomethyl-4-Phthalimido-Pyridine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and reactivity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.