Description

8-Chloro-2,3,4,4A,5,9B-Hexahydro-1H-Pyrido[4,3-B]Indole is a high-purity, advanced pharmaceutical intermediate with the CAS number 954239-28-2. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its unique fused heterocyclic structure. It is essential for research and development chemists and manufacturers in the pharmaceutical and life sciences industries seeking to develop novel therapeutic agents, particularly within central nervous system (CNS) and neurological disorder research.

Application

This versatile intermediate serves as a key precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel psychoactive substances and potential therapeutic agents targeting neurological receptors.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, particularly in the field of CNS disorders.
• Organic Synthesis: Employed in complex multi-step syntheses to construct intricate polycyclic frameworks found in bioactive molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	8-Chloro-2,3,4,4A,5,9B-Hexahydro-1H-Pyrido[4,3-B]Indole
CAS No.	954239-28-2
Molecular Formula	C11H13ClN2
Molecular Weight	208.69 g/mol
Synonyms	8-Chloro-1,2,3,4,4a,9b-hexahydropyrido[4,3-b]indole; 8-Chloro-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole; 1H-Pyrido[4,3-b]indole, 8-chloro-2,3,4,4a,5,9b-hexahydro-; 8-Chloro-1,2,3,4,4a,9b-hexahydro-pyrido[4,3-b]indole; 954239-28-2; 8-Chlorohexahydropyrido[4,3-b]indole
EINECS	Contact for details

Quality Control

Our 8-Chloro-2,3,4,4A,5,9B-Hexahydro-1H-Pyrido[4,3-B]Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH guidelines ensure a reliable supply of this high-value intermediate for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.