Description

3-(Pyridin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core linked to a pyridinyloxy moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes under GMP conditions.
• Ligand and Modifier Synthesis: Utilized for creating specialized ligands for catalysis or molecular modifiers in chemical biology.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.
• Academic Research: Employed in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	3-(Pyridin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	954228-57-0
Molecular Formula	C15H22N2O3
Molecular Weight	278.35 g/mol
Synonyms	1-Boc-3-(pyridin-4-yloxy)piperidine; tert-Butyl 3-(pyridin-4-yloxy)piperidine-1-carboxylate; 3-(4-Pyridyloxy)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(4-pyridyloxy)piperidine; 3-(4-Pyridinyloxy)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 954228-57-0; Boc-3-(4-Pyridyloxy)piperidine
EINECS	Contact for details

Quality Control

Our 3-(Pyridin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.