Description

3-(3-Chlorobenzyl)Piperidine is a versatile and high-purity organic building block, specifically a substituted piperidine derivative, essential for advanced synthetic chemistry. This compound matters as a critical intermediate in the research and development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the creation of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing pharmacologically relevant scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, receptor modulators, and enzyme inhibitors.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and insecticides where the chlorobenzyl-piperidine moiety imparts specific biological activity.
• Ligand & Catalyst Preparation: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or linker in the design of chemical probes and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Investigated as a monomer or functional additive in the development of specialty polymers with unique properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	3-(3-Chlorobenzyl)Piperidine
CAS No.	954220-38-3
Molecular Formula	C12H16ClN
Molecular Weight	209.72 g/mol
Synonyms	3-[(3-Chlorophenyl)methyl]piperidine; 1-(3-Chlorobenzyl)piperidin-3-amine (tautomer consideration); 3-(3-Chlorobenzyl)piperidine; Piperidine, 3-[(3-chlorophenyl)methyl]-; 954220-38-3; 3-(m-Chlorobenzyl)piperidine
EINECS	Contact for details

Quality Control

Our 3-(3-Chlorobenzyl)Piperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.