Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile, 5-Chloro-2-Methyl- is a high-value, heterocyclic organic building block with significant utility in advanced chemical synthesis. This compound is a key intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials, offering a versatile scaffold for molecular diversification. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Synthesis: A versatile synthon for constructing complex fused-ring systems in academic and industrial research laboratories.
• Bioconjugation & Probe Development: The nitrile and chloro functional groups allow for further derivatization to create biochemical probes and labeling agents.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile, 5-Chloro-2-Methyl-
CAS No.	954112-83-5
Molecular Formula	C9H6ClN3
Molecular Weight	191.62 g/mol
Synonyms	5-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile; 5-Chloro-2-methyl-7-azaindole-3-carbonitrile; 5-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile; 954112-83-5; 5-Chloro-2-methyl-7-aza-1H-indole-3-carbonitrile; 5-Chloro-2-methyl-1H-7-azaindole-3-carbonitrile; 5-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile, 5-Chloro-2-Methyl- adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.