Description

(S)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine Hydrochloride CAS NO 953780-70-6 is a high-purity chiral amine building block, specifically the hydrochloride salt of the (S)-enantiomer. This compound is a critical intermediate in modern pharmaceutical research and development, valued for its defined stereochemistry and functional group compatibility. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis to create other enantiomerically pure compounds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Process Chemistry: Utilized in route scouting and optimization for the scalable manufacturing of chiral active ingredients.
• Academic Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry within university and institutional labs.

Basic Information

Product Name	(S)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine Hydrochloride
CAS No.	953780-70-6
Molecular Formula	C7H10BrClN2
Molecular Weight	237.52 g/mol
Synonyms	(S)-1-(5-Bromopyridin-2-yl)ethan-1-amine hydrochloride; (S)-1-(5-Bromo-2-pyridinyl)ethylamine hydrochloride; (S)-α-Methyl-5-bromo-2-pyridineethanamine hydrochloride; (S)-5-Bromo-2-(1-aminoethyl)pyridine hydrochloride; (1S)-1-(5-Bromopyridin-2-yl)ethanamine hydrochloride; (S)-1-(5-Bromo-2-pyridyl)ethylamine HCl
EINECS	Contact for details

Quality Control

Our (S)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet the high standards required for research and development. Certificates of Analysis (COA) detailing specific results for chiral purity (HPLC), assay, and related substances are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.