Description

(R)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine is a high-value chiral amine building block featuring a brominated pyridine core. This compound is critical for the synthesis of complex molecules where stereochemistry and specific halogen substitution are essential for biological activity and material properties. It is primarily utilized by pharmaceutical and agrochemical R&D departments, as well as by fine chemical manufacturers specializing in custom synthesis and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the bromo-pyridine moiety for bioactivity.
• Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.

Basic Information

Product Name	(R)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine
CAS No.	953780-20-6
Molecular Formula	C7H9BrN2
Molecular Weight	201.07 g/mol
Synonyms	(R)-1-(5-Bromopyridin-2-yl)ethan-1-amine; (R)-α-Methyl-5-bromo-2-pyridinemethanamine; (R)-5-Bromo-2-(1-aminoethyl)pyridine; (R)-1-(5-Bromo-2-pyridinyl)ethylamine; (R)-5-Bromo-2-(α-aminoethyl)pyridine; (R)-2-(1-Aminoethyl)-5-bromopyridine; (R)-1-(5-Bromopyridin-2-yl)ethylamine; (R)-5-Bromo-2-pyridineethanamine, α-methyl-
EINECS	Contact for details

Quality Control

Our (R)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.