Description

3-Chloro-1-{4H,5H,6H,7H-Thieno-[3,2-C]Pyridin-5-Yl}Propan-1-One is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 953757-10-3. This heterocyclic compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Serves as a building block for developing new-generation pesticides and herbicides with specific biological activity.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new heterocyclic chemistry and reaction pathways.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up production of specific APIs requiring the thienopyridine scaffold.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Chloro-1-{4H,5H,6H,7H-Thieno-[3,2-C]Pyridin-5-Yl}Propan-1-One
CAS No.	953757-10-3
Molecular Formula	C10H10ClNOS
Molecular Weight	227.71 g/mol
Synonyms	3-Chloro-1-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)propan-1-one; 3-Chloro-1-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-1-propanone; 953757-10-3; Thieno[3,2-c]pyridine-5(4H,6H,7H)-propanone, 3-chloro-1-; 3-Chloropropyl 4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl ketone
EINECS	Contact for details

Quality Control

Our 3-Chloro-1-{4H,5H,6H,7H-Thieno-[3,2-C]Pyridin-5-Yl}Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.