Description

3-Pyridinecarboxylic Acid, 5-Chloro-6-(2,2,2-Trifluoroethoxy)- is a high-value, multi-functional heterocyclic building block characterized by its pyridine core and trifluoroethoxy substituent. This compound is essential for advanced organic synthesis, offering a unique combination of halogen and fluorine atoms that are critical for modulating the physicochemical properties of target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides and pesticides, where the trifluoroethoxy group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocycles.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 5-Chloro-6-(2,2,2-Trifluoroethoxy)-
CAS No.	953729-63-0
Molecular Formula	C8H5ClF3NO3
Molecular Weight	255.58 g/mol
Synonyms	5-Chloro-6-(2,2,2-trifluoroethoxy)nicotinic acid; 5-Chloro-6-(trifluoroethoxy)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-chloro-6-(2,2,2-trifluoroethoxy)-; 5-Chloro-6-(2,2,2-trifluoroethoxy)nicotinate; Nicotinic acid, 5-chloro-6-(trifluoroethoxy)-; 953729-63-0; 5-Chloro-6-trifluoroethoxynicotinic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarboxylic Acid, 5-Chloro-6-(2,2,2-Trifluoroethoxy)- is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.