Description

1H-Indole-1,7-Dicarboxylic Acid, 2-Borono-, 1-(1,1-Dimethylethyl) 7-Methyl Ester is a specialized, high-value boronic acid ester derivative of indole, serving as a critical building block in modern synthetic organic chemistry. Its unique structure, featuring both carboxylic acid protecting groups and a boronate functionality, makes it an essential precursor for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and complex heterocyclic compounds.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and insecticides with targeted modes of action.
• Material Science: Precursor for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Academic & Industrial R&D: Employed in methodological development and the synthesis of complex natural product analogs or novel chemical libraries.

Basic Information

Product Name	1H-Indole-1,7-Dicarboxylic Acid, 2-Borono-, 1-(1,1-Dimethylethyl) 7-Methyl Ester
CAS No.	953411-05-7
Molecular Formula	C16H18BNO6
Molecular Weight	331.13 g/mol
Synonyms	2-Borono-1H-indole-1,7-dicarboxylic acid 1-tert-butyl 7-methyl ester; 1-(tert-Butyl) 7-methyl 2-borono-1H-indole-1,7-dicarboxylate; tert-Butyl methyl 2-boronobenzene-1,7-dicarboxylate (indole form); Boronic acid, B-(1,7-bis[(1,1-dimethylethyl)methyl ester]-1H-indol-2-yl)-; 953411-05-7; 2-Boronated indole-1,7-diester; Indole-2-boronic acid pinacol ester derivative
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-1,7-Dicarboxylic Acid, 2-Borono-, 1-(1,1-Dimethylethyl) 7-Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive cross-coupling applications. All batches are analyzed using advanced spectroscopic and chromatographic techniques (NMR, HPLC, LC-MS). A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.