Description

1H-Indole-1,4-Dicarboxylic Acid, 2-Borono-, 1-(1,1-Dimethylethyl) 4-Methyl Ester is a sophisticated boronic acid ester derivative of indole, serving as a critical building block in modern synthetic chemistry. This compound is valued for its unique molecular architecture, which combines an indole core with a boronate ester functional group, enabling precise cross-coupling reactions. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules and novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific indole-based scaffolds.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic electronic materials and polymers.
• Chemical Biology Probes: Utilized in the creation of tagged molecules and inhibitors for studying biological pathways and enzyme functions.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel ligands used in asymmetric catalysis.
• Academic & Contract Research: Essential reagent for methodological development and complex molecule synthesis in university and CRO laboratories.

Basic Information

Product Name	1H-Indole-1,4-Dicarboxylic Acid, 2-Borono-, 1-(1,1-Dimethylethyl) 4-Methyl Ester
CAS No.	953411-03-5
Molecular Formula	C16H20BNO6
Molecular Weight	333.15 g/mol
Synonyms	tert-Butyl 2-borono-1,4-dicarboxylate-1H-indole-4-methyl ester; 2-Boronoterephthalic Acid 1-tert-Butyl 4-Methyl Ester Indole Derivative; 1-(tert-Butyl) 4-methyl 2-borono-1H-indole-1,4-dicarboxylate; Boronic acid, B-[1,4-bis[(1,1-dimethylethoxy)carbonyl]-1H-indol-2-yl]-; 953411-03-5; 2-Boronylindole-1,4-dicarboxylic acid 1-tert-butyl 4-methyl ester
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-1,4-Dicarboxylic Acid, 2-Borono-, 1-(1,1-Dimethylethyl) 4-Methyl Ester is produced and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request, providing full traceability and supporting cGMP-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.