Description

5-Boc -4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group, making it a critical building block for complex organic synthesis. This compound is essential for research and development in medicinal chemistry, particularly for creating novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily sought after by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the development of new drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug molecules, particularly those targeting the central nervous system (CNS) and oncology.
• API Development: Serves as a crucial building block for constructing the core scaffold of novel Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Protease Inhibitor Synthesis: The imidazopyridine core structure is valuable in the development of protease inhibitors for various disease targets.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Scale-Up: An important starting material for custom synthesis projects, from milligram-scale research to kilogram-scale commercial production.

Basic Information

Product Name	5-Boc -4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine-6-Carboxylic Acid
CAS No.	953061-59-1
Molecular Formula	C₁₂H₁₇N₃O₄
Molecular Weight	267.28 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)amino]-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid; 6-Carboxy-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxylic acid tert-butyl ester; 5-Boc-amino-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid; Boc-ATIP-6-COOH; tert-Butyl 6-carboxy-3,4,6,7-tetrahydroimidazo[4,5-c]pyridine-5(1H)-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Boc -4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine-6-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.