Description

5-Benzyloxy-Pyridin-2-Ylamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a versatile synthon for constructing complex molecules, particularly in medicinal chemistry and advanced material science. This compound is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its pyridine-based structure.
• Chemical Synthesis: Serves as a protected amine precursor for introducing the 2-aminopyridine moiety into more complex molecular architectures.
• Material Science: Potential monomer or ligand in the development of functional polymers and metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	5-Benzyloxy-Pyridin-2-Ylamine Hydrochloride
CAS No.	953045-50-6
Molecular Formula	C12H13N2O·HCl
Molecular Weight	236.71 g/mol
Synonyms	2-Amino-5-(benzyloxy)pyridine hydrochloride; 5-(Benzyloxy)pyridin-2-amine hydrochloride; 5-Benzyloxy-2-aminopyridine HCl; 2-Pyridinamine, 5-(phenylmethoxy)-, hydrochloride (1:1); 5-(Phenylmethoxy)pyridin-2-amine hydrochloride; 5-O-Benzyl-2-aminopyridine hydrochloride; 5-BnO-2-APy·HCl
EINECS	Contact for details

Quality Control

Our 5-Benzyloxy-Pyridin-2-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.