Description

3-Chloro-5-Iodopyridin-2-Amine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional halogen pattern enables selective cross-coupling reactions and further functionalization, making it indispensable for creating complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for studying biological systems.
• Cross-Coupling Reactions: The iodine and chlorine substituents allow for sequential, site-selective Suzuki, Stille, or Buchwald-Hartwig amination reactions.

Basic Information

Product Name	3-Chloro-5-Iodopyridin-2-Amine
CAS No.	952901-62-1
Molecular Formula	C5H4ClIN2
Molecular Weight	254.45 g/mol
Synonyms	2-Amino-3-chloro-5-iodopyridine; 3-Chloro-5-iodopyridin-2-ylamine; 5-Iodo-3-chloropyridin-2-amine; 3-Chloro-5-iodo-2-pyridinamine; 2-Pyridinamine, 3-chloro-5-iodo-; 3-Chloro-5-iodo-2-aminopyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-Iodopyridin-2-Amine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and other relevant analytical methods. Our quality commitment ensures the material meets the stringent requirements for research and development applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.