Description

Methyl 3-Bromo-6-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and developers seeking to incorporate a halogenated, trifluoromethylated pyrrolopyridine scaffold into novel molecular architectures. It is primarily utilized in the pharmaceutical and agrochemical industries for the research and development of new active ingredients, where its unique structure enables the fine-tuning of biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and antiviral research.
• Agrochemical Research: Serves as a sophisticated building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the research of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a probe or labeling agent in biochemical assays and proteomics research.
• Custom Synthesis: An essential starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Library Synthesis: Used in combinatorial and parallel synthesis to create diverse chemical libraries for high-throughput screening.

Basic Information

Product Name	Methyl 3-Bromo-6-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate
CAS No.	952800-37-2
Molecular Formula	C10H6BrF3N2O2
Molecular Weight	323.07 g/mol
Synonyms	Methyl 3-bromo-6-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 3-Bromo-6-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-bromo-6-(trifluoromethyl)-, methyl ester; Methyl 3-bromo-6-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 952800-37-2; CAS 952800-37-2
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Bromo-6-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.