Description

Spiro[2H-1-Benzopyran-2,4'-Piperidine]-4-Acetic Acid, 1'-[(1,1-Dimethylethoxy)Carbonyl]-3,4-Dihydro-, Ethyl Ester is a sophisticated spirocyclic organic compound that serves as a critical synthetic intermediate in advanced chemical synthesis. Its unique molecular architecture, featuring a benzopyran ring fused to a protected piperidine moiety, makes it a valuable building block for constructing complex pharmacologically active molecules. This high-purity intermediate is primarily utilized by pharmaceutical R&D and fine chemical manufacturers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Organic Synthesis Building Block: Used in constructing complex spirocyclic and heterocyclic frameworks for medicinal chemistry and material science research.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new chemical spaces.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural unit in the development of new therapeutic agents.
• Process Chemistry: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Item	Detail
Product Name	Spiro[2H-1-Benzopyran-2,4'-Piperidine]-4-Acetic Acid, 1'-[(1,1-Dimethylethoxy)Carbonyl]-3,4-Dihydro-, Ethyl Ester
CAS No.	952681-81-1
Molecular Formula	C22H29NO5
Molecular Weight	387.47 g/mol
Synonyms	Ethyl 1'-[(tert-Butoxycarbonyl)-3,4-dihydrospiro[2H-1-benzopyran-2,4'-piperidine]-4-acetate; tert-Butyl 4-(2-ethoxy-2-oxoethyl)-3,4-dihydro-2H-spiro[1-benzopyran-2,4'-piperidine]-1'-carboxylate; Boc-protected Spirobenzopyran-piperidine Ethyl Ester; 1'-Boc-3,4-dihydrospiro[chromene-2,4'-piperidine]-4-acetic Acid Ethyl Ester; CAS 952681-81-1
EINECS	Contact for details

Quality Control

Our production of Spiro[2H-1-Benzopyran-2,4'-Piperidine]-4-Acetic Acid, 1'-[(1,1-Dimethylethoxy)Carbonyl]-3,4-Dihydro-, Ethyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.