Description

1-Phenyl-2-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1H-Benzimidazole is a high-value, advanced pharmaceutical intermediate and building block in organic synthesis. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those containing benzimidazole and biaryl motifs with potential biological activity.
• Suzuki-Miyaura Cross-Coupling Reagent: Essential boron-containing partner for palladium-catalyzed carbon-carbon bond formation, enabling the synthesis of complex, functionalized organic molecules.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides that require specific aromatic architectures.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for creating electron-transport or host materials in advanced display and lighting technologies.
• Ligand Synthesis: Can be utilized to develop novel ligands for catalysis or metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A versatile tool for methodological development and exploring new chemical spaces in synthetic chemistry laboratories.

Basic Information

Product Name	1-Phenyl-2-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1H-Benzimidazole
CAS No.	952514-86-2
Molecular Formula	C25H25BN2O2
Molecular Weight	396.29 g/mol
Synonyms	2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1-phenyl-1H-benzimidazole; 1-Phenyl-2-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-benzo[d]imidazole; Benzimidazole, 1-phenyl-2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 952514-86-2; PINAP Boronate Ester; (1-Phenyl-1H-benzimidazol-2-yl)phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Phenyl-2-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1H-Benzimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.