Description

2-Chloro-4-Methylthieno[3,4-B]Pyridine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its crucial role in the synthesis of complex molecules, particularly in medicinal chemistry for developing new therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries engaged in innovative R&D and fine chemical production.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its unique thienopyridine scaffold for biological activity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic and Contract Research: A valuable reagent for synthetic organic chemistry research in academic and industrial R&D laboratories.

Basic Information

Item	Details
Product Name	2-Chloro-4-Methylthieno[3,4-B]Pyridine
CAS No.	952435-07-3
Molecular Formula	C8H6ClNS
Molecular Weight	183.66 g/mol
Synonyms	2-Chloro-4-methylthieno[3,4-b]pyridine; 2-Chloro-4-methylthieno[3,4-b]pyridine; 952435-07-3; Thieno[3,4-b]pyridine, 2-chloro-4-methyl-; 4-Methyl-2-chlorothieno[3,4-b]pyridine; 2-Chloro-4-methyl-thieno[3,4-b]pyridine; 2-Chloro-4-methylthieno[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methylthieno[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.