Description

1H-Imidazole-1-Sulfonyl Azide is a specialized organic azide reagent primarily used as a versatile diazo transfer agent in synthetic organic chemistry. This compound is critical for introducing azide functional groups into target molecules, enabling the synthesis of complex heterocycles and facilitating click chemistry reactions. It is an essential building block for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise functionalization is required.

Application

• Diazo Transfer Reagent: Key for the efficient synthesis of α-diazocarbonyl compounds from active methylene compounds.
• Click Chemistry Precursor: Used to generate azide intermediates for subsequent copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Pharmaceutical Intermediate: Enables the construction of nitrogen-rich heterocyclic scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the development of novel herbicides and fungicides with specific modes of action.
• Polymer Functionalization: Used to modify polymer backbones with azide groups for creating advanced materials with tailored properties.
• Bioconjugation: Facilitates the labeling and cross-linking of biomolecules for diagnostic and research applications.

Basic Information

Product Name	1H-Imidazole-1-Sulfonyl Azide
CAS No.	952234-37-6
Molecular Formula	C3H3N5O2S
Molecular Weight	173.15 g/mol
Synonyms	Imidazole-1-sulfonyl azide; Imidazole-1-sulfonyl azide hydrochloride; ISA; Imidazylsulfonyl azide; 1-(Azidosulfonyl)-1H-imidazole; 1H-Imidazole-1-sulfonyl azide; Imidazol-1-ylsulfonyl azide
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-1-Sulfonyl Azide is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and IR spectroscopy results. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent decomposition. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.