Description

2-Nitrophenyl Azide is a specialized aromatic azide compound, recognized by the CAS number 1516-58-1. This chemical serves as a critical photoaffinity labeling reagent and a versatile building block in synthetic organic chemistry. It is primarily utilized by research institutions and industrial R&D departments focused on developing pharmaceuticals, agrochemicals, and advanced materials. Its unique reactivity under photochemical conditions makes it indispensable for probing biological interactions and constructing complex molecular architectures.

Application

• Photoaffinity Labeling: A key reagent for covalently tagging biological targets (e.g., proteins, enzymes) to study binding sites and molecular interactions under UV light.
• Click Chemistry: Serves as a precursor for generating nitrenes, which can participate in cycloaddition reactions for bioconjugation and polymer functionalization.
• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those containing heterocyclic or labeled structures for metabolic studies.
• Material Science Research: Employed in the surface modification of polymers and the development of photo-crosslinkable materials and coatings.
• Agrochemical Development: Acts as an intermediate in creating active ingredients for crop protection agents with specific modes of action.
• Chemical Biology Probes: Integral for designing activity-based probes to visualize and understand enzymatic functions within cells.

Basic Information

Product Name	2-Nitrophenyl Azide
CAS No.	1516-58-1
Molecular Formula	C6H4N4O2
Molecular Weight	164.12 g/mol
Synonyms	o-Nitrophenyl azide; 1-Azido-2-nitrobenzene; 2-Nitro-1-azidobenzene; (2-Nitrophenyl)azide; Azidobenzene, 2-nitro-; NSC 406916; 2-Nitrobenzenazide
EINECS	Contact for details

Quality Control

Our 2-Nitrophenyl Azide is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.