Description

2-{4-[1,3-Dimethyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-6-Yl]Piperazino}-1-Ethanol is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is valued for its complex heterocyclic structure, which incorporates a trifluoromethyl group and a piperazine-ethanol moiety, offering unique reactivity and potential for creating targeted drug molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially for targeted therapies.
• Oncology Research: Used in the synthesis of potential anti-cancer agents due to its complex pyrazolopyridine core structure.
• CNS Drug Discovery: Serves as a precursor in the development of compounds targeting neurological disorders.
• Chemical Biology: Employed as a molecular probe or scaffold in studying protein-ligand interactions and biological pathways.
• Process Chemistry: Utilized in route scouting and optimization for the scalable synthesis of complex molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2-{4-[1,3-Dimethyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-6-Yl]Piperazino}-1-Ethanol
CAS No.	952183-75-4
Molecular Formula	C15H20F3N5O
Molecular Weight	343.35 g/mol
Synonyms	1,3-Dimethyl-4-(trifluoromethyl)-6-(4-(2-hydroxyethyl)piperazin-1-yl)-1H-pyrazolo[3,4-b]pyridine; 6-[4-(2-Hydroxyethyl)piperazin-1-yl]-1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine; 2-(4-(1,3-Dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl)piperazin-1-yl)ethanol; 1H-Pyrazolo[3,4-b]pyridine, 6-[4-(2-hydroxyethyl)-1-piperazinyl]-1,3-dimethyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-{4-[1,3-Dimethyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-6-Yl]Piperazino}-1-Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.