Description

3-(4-Chlorobenzyl)-3-Formylpiperidine, n-Boc Protected is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group. This compound is critical for the synthesis of complex molecules, offering chemists a stable and reactive building block for constructing novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of targeted therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries via further functionalization of the formyl and protected amine groups.
• Process Chemistry & Scale-up: Employed in the development and optimization of robust synthetic routes for API manufacturing under GMP conditions.
• Peptidomimetic Synthesis: Acts as a constrained, non-natural amino acid analog for designing bioactive peptides with enhanced stability and potency.
• Agrochemical Research: Utilized in the discovery and synthesis of new active ingredients for crop protection products.

Basic Information

Product Name	3-(4-Chlorobenzyl)-3-Formylpiperidine, n-Boc Protected
CAS No.	952183-49-2
Molecular Formula	C18H24ClNO3
Molecular Weight	337.84 g/mol
Synonyms	1-Boc-3-(4-Chlorobenzyl)-3-formylpiperidine; tert-Butyl 3-(4-chlorobenzyl)-3-formylpiperidine-1-carboxylate; 3-Formyl-3-(4-chlorobenzyl)piperidine-1-carboxylic acid tert-butyl ester; 3-(p-Chlorobenzyl)-3-formyl-1-N-Boc-piperidine; N-Boc-3-(4-chlorobenzyl)-3-formylpiperidine; 1-(tert-Butoxycarbonyl)-3-(4-chlorobenzyl)-3-formylpiperidine; 3-(4-Chlorophenyl)methyl-3-formyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorobenzyl)-3-Formylpiperidine, n-Boc Protected is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.