Description

6-(Trifluoromethyl)Furo[2,3-B]Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block prized for its unique trifluoromethyl-substituted fused ring system. This compound is essential for medicinal chemistry research and development, enabling the synthesis of novel molecules with enhanced metabolic stability and binding affinity. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for creating next-generation active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly in oncology, CNS disorders, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the furopyridine scaffold.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	6-(Trifluoromethyl)Furo[2,3-B]Pyridine-2-Carboxylic Acid
CAS No.	952182-47-7
Molecular Formula	C9H4F3NO3
Molecular Weight	231.13 g/mol
Synonyms	6-(Trifluoromethyl)furo[2,3-b]pyridine-2-carboxylic acid; 2-Furoic acid, 6-(trifluoromethyl)furo[2,3-b]pyridine-; 6-Trifluoromethylfuro[2,3-b]pyridine-2-carboxylic acid; Furo[2,3-b]pyridine-2-carboxylic acid, 6-(trifluoromethyl)-; 952182-47-7; 6-(Trifluoromethyl)-2-furo[2,3-b]pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-(Trifluoromethyl)Furo[2,3-B]Pyridine-2-Carboxylic Acid adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high purity suitable for advanced synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We maintain traceability and documentation practices that support development under quality management systems, including ISO and cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.