Description

Methyl 3-Bromo-1H-Pyrrolo-[3,2-B]Pyridine-2-Carboxylate is a high-value brominated heterocyclic building block, specifically a functionalized pyrrolopyridine derivative, essential for advanced organic synthesis. This compound matters because it serves as a critical precursor for constructing complex molecular architectures, enabling the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and scaffold diversification.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in developing novel active ingredients for crop protection by serving as a core heterocyclic scaffold.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-rich fused ring system.
• Chemical Biology: Acts as a versatile probe or labeling agent for studying biological pathways and protein interactions.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	Methyl 3-Bromo-1H-Pyrrolo-[3,2-B]Pyridine-2-Carboxylate
CAS No.	952182-30-8
Molecular Formula	C9H7BrN2O2
Molecular Weight	255.07 g/mol
Synonyms	Methyl 3-bromo-1H-pyrrolo[3,2-b]pyridine-2-carboxylate; 3-Bromo-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid methyl ester; 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, 3-bromo-, methyl ester; Methyl 3-bromo-7-azaindole-2-carboxylate; 3-Bromo-7-azaindole-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-1H-Pyrrolo-[3,2-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.