Description

Methyl 5-Amino-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is a high-purity, heterocyclic organic building block of significant importance in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for constructing complex molecular architectures, particularly in medicinal chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel heterocyclic compounds in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential herbicidal or pesticidal activity.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and organic electronic materials.

Basic Information

Product Name	Methyl 5-Amino-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate
CAS No.	952182-18-2
Molecular Formula	C9H9N3O2
Molecular Weight	191.19 g/mol
Synonyms	5-Amino-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; Methyl 5-aminopyrrolo[2,3-b]pyridine-2-carboxylate; 5-Amino-1H-pyrrolo[2,3-b]pyridine-2-carboxylate, methyl ester; 952182-18-2; 5-Amino-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Amino-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP standards for early-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.