Description

Methyl 5-Nitro-7-Azaindole-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its nitro-substituted azaindole core structure. This compound is of significant value for its role as a key building block in the synthesis of complex heterocyclic molecules, particularly in medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for creating novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug molecules, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex fused heterocyclic systems due to its reactive nitro and ester functional groups.
• Agrochemical Research: Employed in the discovery and development of new agrochemicals, such as herbicides and fungicides, leveraging its heterocyclic architecture.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	Methyl 5-Nitro-7-Azaindole-2-Carboxylate
CAS No.	952182-17-1
Molecular Formula	C9H7N3O4
Molecular Weight	221.17 g/mol
Synonyms	Methyl 5-nitro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-nitro-, methyl ester; 5-Nitro-7-azaindole-2-carboxylic acid methyl ester; Methyl 5-nitro-7-azaindole-2-carboxylate; 952182-17-1; 5-Nitro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Nitro-7-Azaindole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.