Description

1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Serves as a versatile building block for creating tool compounds to study biological pathways and protein functions.
• Material Science Applications: Potential use in the synthesis of organic electronic materials, ligands for catalysis, and advanced polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and process development projects.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid
CAS No.	952182-02-4
Molecular Formula	C7H5N3O2
Molecular Weight	163.14 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid; Pyrazolo[3,4-b]pyridine-5-carboxylic acid; 5-Carboxy-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid; 952182-02-4; 5-Pyrazolo[3,4-b]pyridinecarboxylic acid; 1H-1,2,3-Triazolo[4,5-b]pyridine-5-carboxylic acid (tautomer); Pyrazolopyridine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid is manufactured under strict quality management systems. We provide material with typical purity grades suitable for research and development, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, ensuring full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The material may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical grade)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.