Description

1,6-Naphthyridine, 4,7-Dichloro- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its rigid, fused-ring structure and reactive halogen substituents, making it a critical precursor for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its bioactive heterocyclic core.
• Ligand Synthesis: Acts as a precursor for creating sophisticated chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials, such as semiconductors and light-emitting components.
• Chemical Biology Probes: Utilized to build molecular tools for studying biological processes and enzyme functions.
• Cross-Coupling Reactions: The chloro substituents make it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, and Buchwald-Hartwig amination.

Basic Information

Product Name	1,6-Naphthyridine, 4,7-Dichloro-
CAS No.	952138-13-5
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.04 g/mol
Synonyms	4,7-Dichloro-1,6-naphthyridine; 4,7-Dichloro-1,6-naphthyridine; 1,6-Naphthyridine, 4,7-dichloro-; 4,7-Dichloro[1,6]naphthyridine; Dichloronaphthyridine; 4,7-Dichloro-1,6-naphthyridine (major); 1,6-Naphthyridine,4,7-dichloro-
EINECS	Contact for details

Quality Control

Our 1,6-Naphthyridine, 4,7-Dichloro- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder/crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.