Description

n-[3-(1,3-Benzoxazol-2-Yl)-4-Hydroxyphenyl]-3-Bromo-4-Ethoxybenzamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its precise molecular architecture, which serves as a critical building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and targeted drug discovery programs.

Application

• Key intermediate in the research and synthesis of novel small-molecule drug candidates.
• Building block for the development of kinase inhibitors and other targeted cancer therapies.
• Precursor in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Used in academic and industrial R&D for exploring new pharmacophores containing benzoxazole and bromo-ethoxybenzamide motifs.
• Critical component in the scale-up and process development for new chemical entities (NCEs).
• Reference standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	n-[3-(1,3-Benzoxazol-2-Yl)-4-Hydroxyphenyl]-3-Bromo-4-Ethoxybenzamide
CAS No.	951995-33-8
Molecular Formula	C22H17BrN2O4
Molecular Weight	453.29 g/mol
Synonyms	3-Bromo-4-ethoxy-N-[3-(2-benzoxazolyl)-4-hydroxyphenyl]benzamide; 951995-33-8; Benzamide, N-[3-(2-benzoxazolyl)-4-hydroxyphenyl]-3-bromo-4-ethoxy-; 3-Bromo-4-ethoxy-N-[4-hydroxy-3-(1,3-benzoxazol-2-yl)phenyl]benzamide; 3-Bromo-4-ethoxy-N-[3-(1,3-benzoxazol-2-yl)-4-hydroxyphenyl]benzamide; N-(3-(Benzo[d]oxazol-2-yl)-4-hydroxyphenyl)-3-bromo-4-ethoxybenzamide
EINECS	Contact for details

Quality Control

Our n-[3-(1,3-Benzoxazol-2-Yl)-4-Hydroxyphenyl]-3-Bromo-4-Ethoxybenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) with full traceability are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.