Description

Ethyl 3-Cyano-4-Fluorobenzoylformate is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its molecular structure, featuring both cyano and fluorobenzoylformate groups, makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily sought by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and specialty polymers where its functional groups can modify electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Product Name	Ethyl 3-Cyano-4-Fluorobenzoylformate
CAS No.	951888-16-7
Molecular Formula	C11H8FNO3
Molecular Weight	221.19 g/mol
Synonyms	Ethyl 3-cyano-4-fluorobenzoylformate; Ethyl (3-cyano-4-fluorophenyl)(oxo)acetate; 3-Cyano-4-fluorobenzoylformic Acid Ethyl Ester; Ethyl α-Oxo-3-cyano-4-fluorobenzeneacetate; 4-Fluoro-3-cyanobenzoylformic Acid Ethyl Ester; Ethyl 4-Fluoro-3-cyanobenzoylformate; Ethyl 2-(3-cyano-4-fluorophenyl)-2-oxoacetate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Cyano-4-Fluorobenzoylformate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring traceability and compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.