Description

n-Cyclopropyl 2-Bromo-4-Pyridinecarboxamide is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to incorporate functionalized pyridine scaffolds into their target compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel crop protection agents and herbicides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Organic Synthesis: Versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to the reactive bromine atom and amide group.
• Material Science Research: Potential monomer or precursor for designing functional organic materials and ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	n-Cyclopropyl 2-Bromo-4-Pyridinecarboxamide
CAS No.	951885-74-8
Molecular Formula	C9H9BrN2O
Molecular Weight	241.09 g/mol
Synonyms	2-Bromo-N-cyclopropylisonicotinamide; 2-Bromo-N-cyclopropyl-4-pyridinecarboxamide; 4-Pyridinecarboxamide, 2-bromo-N-cyclopropyl-; n-Cyclopropyl-2-bromoisonicotinamide; 2-Bromo-4-pyridinecarboxylic acid cyclopropylamide; CP-2B-4-PCA; Cyclopropyl 2-bromopyridine-4-carboxamide
EINECS	Contact for details

Quality Control

Our n-Cyclopropyl 2-Bromo-4-Pyridinecarboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.