Description

2-Chloro-4-Fluoro-6-Iodophenol is a halogenated phenol derivative that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a valuable building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen functionalities into their target structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and cross-coupling reactions.
• Material Science Research: Intermediate for creating halogenated polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes and tags used in biochemical assays and imaging.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production.

Basic Information

Item	Details
Product Name	2-Chloro-4-Fluoro-6-Iodophenol
CAS No.	951671-77-5
Molecular Formula	C6H3ClFIO
Molecular Weight	287.44 g/mol
Synonyms	2-Chloro-4-fluoro-6-iodophenol; 6-Iodo-2-chloro-4-fluorophenol; Phenol, 2-chloro-4-fluoro-6-iodo-; 4-Fluoro-2-chloro-6-iodophenol; 2-Chloro-6-iodo-4-fluorophenol; 951671-77-5 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-6-Iodophenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.