Description

5-Bromo-3-Chloro-1H-Pyrrolo[2,3-B]Pyridine is a high-value halogenated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceuticals and agrochemicals, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the discovery of kinase inhibitors and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for oncology and CNS (Central Nervous System) targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyrrolopyridine core.
• Material Science: Serves as a building block for creating organic electronic materials and functional dyes.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for method development and novel synthetic route exploration.

Basic Information

Product Name	5-Bromo-3-Chloro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	951626-91-8
Molecular Formula	C7H4BrClN2
Molecular Weight	247.48 g/mol
Synonyms	5-Bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-5-bromo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-3-chloro-; 5-Bromo-3-chloro-7-azaindole; 3-Chloro-5-bromo-7-azaindole; 5-Br-3-Cl-7-azaindole; 5-Bromo-3-chloro-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Chloro-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP (current Good Manufacturing Practice) guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.