Description

Methyl 4-Chloro-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylate is a high-purity, heterocyclic organic building block of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the creation of targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Potential building block for developing new, high-performance crop protection agents with specific modes of action.
• Material Science: Can be utilized in the research of organic electronic materials due to its fused heterocyclic structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Methyl 4-Chloro-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylate
CAS No.	951625-93-7
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester; Methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 4-chloro-, methyl ester; 951625-93-7; 4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester; 4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.