Description

5-[[(4-Fluorophenyl)Methyl]Amino]-1,3-Dihydro-2H-Imidazo[4,5-B]Pyridin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its imidazopyridine core structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapeutics, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors and other targeted small molecules.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Reagent: Used in biochemical assays and as a reference standard for analytical method development and validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and pharmacology.

Basic Information

Product Name	5-[[(4-Fluorophenyl)Methyl]Amino]-1,3-Dihydro-2H-Imidazo[4,5-B]Pyridin-2-One
CAS No.	951624-49-0
Molecular Formula	C14H11FN4O
Molecular Weight	270.26 g/mol
Synonyms	5-[(4-Fluorobenzyl)amino]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one; 5-((4-Fluorobenzyl)amino)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one; 951624-49-0; UNII-6K7J8Q3B3F; 6K7J8Q3B3F; CHEMBL3185146; BDBM50151751; AKOS005209156
EINECS	Contact for details

Quality Control

Our 5-[[(4-Fluorophenyl)Methyl]Amino]-1,3-Dihydro-2H-Imidazo[4,5-B]Pyridin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.