Description

Ethyl 6-((Boc-Amino)Methyl)Nicotinate is a high-purity, protected amino acid derivative and a key nicotinate ester building block. This compound is critical for the synthesis of complex molecules, offering a versatile handle for peptide coupling and further functionalization under mild conditions. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of new active pharmaceutical ingredients (APIs) and biochemical probes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially in oncology and neurology research.
• Peptide Chemistry: Used for the incorporation of modified amino acid residues into peptides, leveraging the Boc-protected amine for orthogonal synthesis strategies.
• Chemical Biology: Serves as a precursor for labeling reagents and activity-based probes to study enzyme function and protein interactions.
• Agrochemical Research: Employed in the discovery and development of new crop protection agents and plant growth regulators.
• Academic & Contract Research: Essential for synthetic organic chemistry projects in universities and contract research organizations (CROs).
• Custom Synthesis: A starting material for the custom manufacturing of specialty chemicals and advanced intermediates for clients.

Basic Information

Product Name	Ethyl 6-((Boc-Amino)Methyl)Nicotinate
CAS No.	951624-36-5
Molecular Formula	C15H22N2O4
Molecular Weight	294.35 g/mol
Synonyms	Ethyl 6-(((tert-Butoxycarbonyl)amino)methyl)nicotinate; 6-((Boc-Aminomethyl))nicotinic Acid Ethyl Ester; tert-Butyl N-[(5-(ethoxycarbonyl)pyridin-2-yl)methyl]carbamate; Boc-AMN-OEt; Ethyl 6-(N-Boc-aminomethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 6-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-((Boc-Amino)Methyl)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.