Description

(Z)-Methyl 2-(Boc-Amino)Nona-2,8-Dienoate CAS NO 951624-21-8 is a high-purity, protected amino acid derivative featuring a Boc-protected amine group and a conjugated diene ester functionality. This compound is a critical advanced pharmaceutical intermediate (API intermediate) used in the synthesis of complex bioactive molecules, offering precise stereochemical control for demanding applications. It is essential for researchers and manufacturers in pharmaceutical development, peptide chemistry, and medicinal chemistry who require reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Mimetics & Conjugate Synthesis: Utilized for introducing protected amino acid motifs with an extended hydrophobic chain, useful in creating peptide-drug conjugates or lipopeptides.
• Medicinal Chemistry & Drug Discovery: Serves as a versatile scaffold in structure-activity relationship (SAR) studies and library synthesis for lead optimization.
• Chemical Biology Probes: Employed in the development of labeled or tagged molecular probes due to its reactive diene and protected amine handles.
• Organic Synthesis: Acts as a substrate in various organic transformations, including cross-coupling reactions and cycloadditions, leveraging its diene system.

Basic Information

Product Name	(Z)-Methyl 2-(Boc-Amino)Nona-2,8-Dienoate
CAS No.	951624-21-8
Molecular Formula	C₁₆H₂₇NO₄
Molecular Weight	297.39 g/mol
Synonyms	Methyl (2Z)-2-[(tert-butoxycarbonyl)amino]nona-2,8-dienoate; Boc-Dienylglycine Methyl Ester (Z-isomer); (Z)-2-(Boc-amino)-2,8-nonadienoic Acid Methyl Ester; tert-Butyl ((1Z)-1-(methoxycarbonyl)-2,8-nonadien-1-yl)carbamate; Methyl 2-[(tert-butoxycarbonyl)amino]-2,8-nonadienoate (Z); (Z)-Boc-Dienylgly-OMe; 951624-21-8; Boc-δ²,⁸-Nonadienyl-Gly-OMe (Z)
EINECS	Contact for details

Quality Control

Our (Z)-Methyl 2-(Boc-Amino)Nona-2,8-Dienoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; ensure storage areas are well-ventilated and separate from incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (Z-isomer)	≥ 98.0% (by HPLC or NMR)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.