Description

3-Piperidin-4-Yl-2-Trifluoromethyl-3H-Imidazo[4,5-B]Pyridine is a high-value, heterocyclic organic compound featuring a fused imidazopyridine core with piperidine and trifluoromethyl substituents. This advanced chemical intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries for lead optimization and active pharmaceutical ingredient (API) manufacturing.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead compound optimization, especially for CNS-targeting drugs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex, high-potency APIs.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for pharmacological studies.
• Fine Chemical Manufacturing: Integrated into the production of specialized, high-value fine chemicals for advanced applications.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and manufacturers for custom synthesis and development projects.

Basic Information

Product Name	3-Piperidin-4-Yl-2-Trifluoromethyl-3H-Imidazo[4,5-B]Pyridine
CAS No.	951544-48-2
Molecular Formula	C12H13F3N4
Molecular Weight	270.26 g/mol
Synonyms	2-(Trifluoromethyl)-3-(4-piperidinyl)-3H-imidazo[4,5-b]pyridine; 3-(Piperidin-4-yl)-2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine; 3H-Imidazo[4,5-b]pyridine, 3-(4-piperidinyl)-2-(trifluoromethyl)-; 951544-48-2; 2-Trifluoromethyl-3-piperidin-4-yl-3H-imidazo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Piperidin-4-Yl-2-Trifluoromethyl-3H-Imidazo[4,5-B]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) are available for every batch and supplied upon request, confirming compliance with customer specifications and industry standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.