Description

n-tert-Butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide is a high-value organoboron building block, specifically a boronic ester derivative of a thiophene sulfonamide. This compound is critical for modern synthetic chemistry, enabling the precise construction of complex molecules through cross-coupling reactions. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing thiophene and sulfonamide pharmacophores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the boronic ester group allows for efficient modular assembly of complex structures.
• Material Science: Serves as a monomer or building block for creating functional polymers and organic electronic materials, such as organic semiconductors.
• Chemical Synthesis: Employed in academic and industrial R&D labs for the preparation of complex, functionalized thiophene derivatives for various applications.
• Ligand & Catalyst Development: The sulfonamide group can act as a coordinating site, making this compound useful in designing novel ligands for catalysis.

Basic Information

Product Name	n-tert-Butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide
CAS No.	951233-59-3
Molecular Formula	C14H24BNO4S2
Molecular Weight	345.28 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(tert-butyl)thiophene-2-sulfonamide; N-tert-Butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide; 2-Thiophenesulfonamide, N-(1,1-dimethylethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; tert-Butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide; B-(5-((tert-Butylsulfamoyl)thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.