Description

2-Chloro-5-Methylisonicotinic Acid is a high-purity pyridine derivative and a versatile chemical intermediate of significant commercial importance. Its unique halogenated and methylated structure makes it a critical building block for synthesizing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical manufacturers for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific biological pathways.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of novel organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A fundamental component for custom chemical synthesis services catering to R&D and pilot-scale production.
• Bioconjugation and Probe Development: Useful in medicinal chemistry for creating molecular probes and bioconjugates for diagnostic applications.

Basic Information

Product Name	2-Chloro-5-Methylisonicotinic Acid
CAS No.	951030-56-1
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	2-Chloro-5-methylpyridine-4-carboxylic acid; 5-Methyl-2-chloroisonicotinic acid; 4-Pyridinecarboxylic acid, 2-chloro-5-methyl-; 2-Chloro-5-methyl-4-pyridinecarboxylic acid; 2-Chloro-5-picolinic acid (ambiguous, specify methyl position); Isonicotinic acid, 2-chloro-5-methyl- derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methylisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.