Description

3-Pyridinecarboxylic Acid, 1,2-Dihydro-5-Iodo-6-Methyl-2-Oxo-1-[3-(Trifluoromethyl)Phenyl]- is a high-purity, complex heterocyclic organic compound featuring a fused pyridinecarboxylic acid core substituted with iodine, methyl, and a 3-(trifluoromethyl)phenyl group. This unique molecular architecture makes it a critical advanced intermediate for pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing targeted molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammatory diseases, or oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes, enzyme inhibitors, or labeled compounds for biochemical and diagnostic research.
• Material Science Research: Potential monomer or precursor for advanced organic electronic materials or liquid crystals due to its rigid, substituted aromatic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical scaffold.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 1,2-Dihydro-5-Iodo-6-Methyl-2-Oxo-1-[3-(Trifluoromethyl)Phenyl]-
CAS No.	950857-36-0
Molecular Formula	C14H9F3INO3
Molecular Weight	423.13 g/mol
Synonyms	1-(3-(Trifluoromethyl)phenyl)-5-iodo-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 5-Iodo-6-methyl-1-[3-(trifluoromethyl)phenyl]-1,2-dihydro-2-oxopyridine-3-carboxylic acid; 1,2-Dihydro-5-iodo-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid; 950857-36-0; AI3-53062; ZINC000103258509; SCHEMBL2334221; AKOS040759232.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere if long-term storage is required to minimize potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.