Description

5-(4-Morpholinylmethyl)Thiophene-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block crucial for modern synthetic chemistry, specifically in cross-coupling reactions. This compound matters because it enables the efficient and precise construction of complex molecular architectures containing both thiophene and morpholine pharmacophores. Pharmaceutical researchers and agrochemical developers need it as a key intermediate for creating novel active ingredients in drug discovery and crop protection programs. Its stability as a pinacol ester makes it a reliable reagent for scalable synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in Suzuki-Miyaura cross-coupling reactions for synthesizing potential drug candidates, particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require the thiophene-morpholine scaffold.
• Material Science Research: Serves as a monomer or precursor in the development of advanced organic electronic materials, such as conductive polymers and organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for catalysis or as a structural component in metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and target engagement.

Basic Information

Product Name	5-(4-Morpholinylmethyl)Thiophene-2-Boronic Acid Pinacol Ester
CAS No.	950603-39-1
Molecular Formula	C15H24BNO3S
Molecular Weight	309.23 g/mol
Synonyms	5-(Morpholin-4-ylmethyl)thiophene-2-boronic acid pinacol ester; 2-(4-Morpholinylmethyl)-5-thienylboronic acid pinacol ester; 5-(Morpholinomethyl)thiophene-2-boronic acid pinacol ester; [5-(Morpholin-4-ylmethyl)thiophen-2-yl]boronic acid pinacol ester; Thiophene-2-boronic acid, 5-[(4-morpholinyl)methyl]-, 1,1-dimethylethyl ester; B-[5-(4-Morpholinylmethyl)-2-thienyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 5-(4-Morpholinylmethyl)Thiophene-2-Boronic Acid Pinacol Ester is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.