Description

(2-(Pyridin-3-Yl)Vinyl)Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a pivotal method for constructing complex carbon-carbon bonds. This compound is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing biaryl and heterobiaryl scaffolds prevalent in drug discovery programs, particularly for kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific pyridinyl-vinyl motifs.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Academic & Contract Research: A fundamental reagent for methodological development in cross-coupling chemistry and organometallic catalysis within R&D laboratories.
• Scale-up Process Chemistry: Suitable for optimization and pilot-scale synthesis of target molecules due to its stability and reactivity profile.

Basic Information

Item	Detail
Product Name	(2-(Pyridin-3-Yl)Vinyl)Boronic Acid Pinacol Ester
CAS No.	950483-20-2
Molecular Formula	C15H20BNO2
Molecular Weight	257.14 g/mol
Synonyms	3-Vinylpyridine-2-boronic acid pinacol ester; 2-(3-Pyridinyl)ethenylboronic acid pinacol ester; (2-(3-Pyridinyl)vinyl)boronic acid pinacol ester; (E/Z)-[2-(Pyridin-3-yl)vinyl]boronic acid pinacol ester; 3-Vinylpyridine-2-boronic acid neopentyl glycol ester (common alternative); Pinacol (2-(pyridin-3-yl)vinyl)boronate; 950483-20-2 (CAS Index Name); Boronic acid, B-[2-(3-pyridinyl)ethenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of (2-(Pyridin-3-Yl)Vinyl)Boronic Acid Pinacol Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR (1H, 13C, 11B), and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) documenting all release specifications are available for each lot and provided with every order to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) for long-term storage or when opening the primary container to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.