Description

4-Pyridin-3-Yl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline-8-Carboxylic Acid CAS NO 950187-45-8 is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly as a key building block for active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on innovation in drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Employed in the synthetic route development for potential new chemical entities (NCEs).
• Biochemical Research: May be utilized as a tool compound or ligand in biochemical assays to study specific enzyme or receptor interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Used in university and institutional laboratories for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	4-Pyridin-3-Yl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline-8-Carboxylic Acid
CAS No.	950187-45-8
Molecular Formula	C22H18N2O2
Molecular Weight	342.40 g/mol
Synonyms	4-(Pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid; 3a,4,5,9b-Tetrahydro-4-(3-pyridinyl)-3H-cyclopenta[c]quinoline-8-carboxylic Acid; 950187-45-8; 4-(3-Pyridinyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid; Cyclopenta[c]quinoline-8-carboxylic acid, 3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our production of 4-Pyridin-3-Yl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline-8-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Our quality system is designed to support regulatory filings and can provide documentation suitable for use in cGMP environments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.