Description

8-Benzyl-3-(Trifluoromethylsulfonyloxy)-8-Azabicyclo[3.2.1]Oct-3-Ene is a specialized bicyclic organic intermediate featuring a reactive triflate leaving group, making it a valuable synthon for advanced organic synthesis. This compound is critical for constructing complex nitrogen-containing molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for building novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of tropane alkaloid analogs and other bioactive nitrogen heterocycles with potential therapeutic applications.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require complex, functionalized bicyclic scaffolds.
• Methodology Development: Serves as a model substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to its reactive triflate group.
• Ligand and Catalyst Synthesis: Precursor for creating novel chiral or achiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Potential intermediate for synthesizing functional monomers or additives for advanced polymeric materials.
• Academic Research: Utilized in universities and research institutes for studying reaction mechanisms and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	8-Benzyl-3-(Trifluoromethylsulfonyloxy)-8-Azabicyclo[3.2.1]Oct-3-Ene
CAS No.	949902-02-7
Molecular Formula	C₁₆H₁₆F₃NO₃S
Molecular Weight	359.36 g/mol
Synonyms	8-Benzyl-3-[(trifluoromethyl)sulfonyl]oxy]-8-azabicyclo[3.2.1]oct-3-ene; 8-Benzyl-3-trifluoromethanesulfonyloxy-8-azabicyclo[3.2.1]oct-3-ene; 8-Benzyl-8-azabicyclo[3.2.1]oct-3-en-3-yl Trifluoromethanesulfonate; 8-Benzyl-3-triflyloxy-8-azabicyclo[3.2.1]oct-3-ene; 8-Benzyl-3-OTf-8-azabicyclo[3.2.1]oct-3-ene; 8-Benzyl-3-trifluoromethylsulfonate-8-azabicyclo[3.2.1]oct-3-ene; 8-Benzyl-3-(trifluoromethanesulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene
EINECS	Contact for details

Quality Control

Our 8-Benzyl-3-(Trifluoromethylsulfonyloxy)-8-Azabicyclo[3.2.1]Oct-3-Ene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening the original container to prevent moisture absorption. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.