Description

3-Pyridinecarboxamide, n-[2-(2-Thienyl)Ethyl]-6-(Trifluoromethyl)- is a specialized heterocyclic compound featuring a pyridine core substituted with a trifluoromethyl group and a thienylethyl carboxamide side chain. This molecular architecture is of significant interest for its potential as a key synthetic intermediate in advanced pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients. The compound's unique structure offers a versatile scaffold for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the trifluoromethyl group for enhanced bioactivity and metabolic stability.
• Chemical Biology Probe: Employed as a molecular tool to study enzyme inhibition or receptor-ligand interactions due to its distinct heterocyclic framework.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring this precise chemical entity.

Basic Information

Product Name	3-Pyridinecarboxamide, n-[2-(2-Thienyl)Ethyl]-6-(Trifluoromethyl)-
CAS No.	949870-64-8
Molecular Formula	C13H11F3N2OS
Molecular Weight	300.30 g/mol
Synonyms	N-[2-(2-Thienyl)ethyl]-6-(trifluoromethyl)-3-pyridinecarboxamide; 6-(Trifluoromethyl)-N-[2-(2-thienyl)ethyl]nicotinamide; 6-(Trifluoromethyl)-N-(2-thiophen-2-ylethyl)pyridine-3-carboxamide; Nicotinamide, N-[2-(2-thienyl)ethyl]-6-(trifluoromethyl)-; 949870-64-8; 3-Pyridinecarboxamide, N-[2-(2-thienyl)ethyl]-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-N-(2-(thiophen-2-yl)ethyl)nicotinamide
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinecarboxamide, n-[2-(2-Thienyl)Ethyl]-6-(Trifluoromethyl)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for research applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.