Description

1H-Pyrrolo[2,3-C]Pyridine-1-Carboxylic Acid, Octahydro-, 1,1-Dimethylethyl Ester, (3Ar,7As)-Rel- is a high-purity, advanced pharmaceutical intermediate belonging to the class of fused bicyclic heterocycles. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where precise chemical structure and reliable purity are paramount for successful drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• API Synthesis: Used as a key chiral building block for constructing complex molecular architectures in Active Pharmaceutical Ingredient (API) manufacturing.
• Neurological Drug Research: Particularly relevant in the research and development of therapeutics targeting neurological disorders and CNS pathways.
• Process Chemistry & Scale-Up: Employed in process optimization and scale-up studies from laboratory to pilot plant and commercial production.
• Chemical Biology Probes: Utilized in the development of specialized chemical probes for studying biological mechanisms and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity intermediates.

Basic Information

Product Name	1H-Pyrrolo[2,3-C]Pyridine-1-Carboxylic Acid, Octahydro-, 1,1-Dimethylethyl Ester, (3Ar,7As)-Rel-
CAS No.	949559-11-9
Molecular Formula	C13H22N2O2
Molecular Weight	238.33 g/mol
Synonyms	rel-(3aR,7aS)-Octahydro-1H-pyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl (3aR,7aS)-octahydro-1H-pyrrolo[2,3-c]pyridine-1-carboxylate; (3aR,7aS)-rel-1-Boc-octahydro-1H-pyrrolo[2,3-c]pyridine; 1-Boc-3a,4,5,6,7,7a-hexahydro-1H-pyrrolo[2,3-c]pyridine; 1-N-Boc-octahydropyrrolo[2,3-c]pyridine; tert-Butyl octahydro-1H-pyrrolo[2,3-c]pyridine-1-carboxylate; Bicyclic pyrrolopyridine derivative; Advanced pharmaceutical intermediate 949559-11-9.
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-C]Pyridine-1-Carboxylic Acid, Octahydro-, 1,1-Dimethylethyl Ester, (3Ar,7As)-Rel- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.