Description

2-Amino-5-Methylphenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, making it ideal for handling and storage in demanding industrial processes. This high-purity intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via cross-coupling chemistry.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the creation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and activity-based protein profiling reagents.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-Amino-5-Methylphenylboronic Acid, Pinacol Ester
CAS No.	948592-80-1
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	2-Amino-5-methylbenzeneboronic acid pinacol ester; 2-Amino-5-methylphenylboronic acid pinacol ester; (2-Amino-5-methylphenyl)boronic acid pinacol ester; 2-Methyl-5-aminophenylboronic acid pinacol ester; 5-Methyl-2-aminophenylboronic acid pinacol ester; Boronic acid, B-(2-amino-5-methylphenyl)-, 1,1-dimethylethyl ester; Pinacol (2-amino-5-methylphenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.