Description

2-Amino-5-Methylphenylboronic Acid is a specialized boronic acid derivative featuring both an amino and a methyl substituent on the aromatic ring. This bifunctional structure makes it a versatile and critical building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system disorders.
• Agrochemical Synthesis: Used to create novel herbicides and fungicides with enhanced efficacy and selectivity.
• Ligand for Catalysis: Serves as a component in designing novel catalysts for asymmetric synthesis and other transition metal-catalyzed reactions.
• Material Science Research: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Utilized in the development of sensors and probes for biological imaging and diagnostic applications.
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura cross-coupling to form biaryl and other carbon-carbon bonds under mild conditions.

Basic Information

Product Name	2-Amino-5-Methylphenylboronic Acid
CAS No.	948592-72-1
Molecular Formula	C7H10BNO2
Molecular Weight	150.97 g/mol
Synonyms	(2-Amino-5-methylphenyl)boronic acid; 5-Methyl-2-aminophenylboronic acid; 2-Amino-5-methylbenzeneboronic acid; Boronic acid, B-(2-amino-5-methylphenyl)-; 2-Amino-5-methylphenyl-B(OH)2; 2-Amino-p-tolylboronic acid; 5-Methylanthranilic acid boronate
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Methylphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.